In this bold edition we talk about weight loss drugs – are they healthcare products, an NHS saviour or a complex cosmetic project? We also follow the astonishing and seemingly unstoppable acceleration of AI and the instant impact it is having on industry marketing, the use of data and humankind itself. Features on future innovation, decoding Parkinson’s disease, pharmacovigilance, the link between animal and public health, a review of our International Clinical Researcher of the Year Awards and what decisions must be made about the NHS, complete a tubthumping edition of pharma’s most intrepid periodical.